From the frontlines of immunotherapy


Chimeric antigen receptor T-cell (CAR-T) immunotherapies are transforming leukemia therapy. My Lovely And Talented Wife® has been working with the FDA on CAR-T trials at Washington University. Now, they appear to be providing transformative results with autoimmune disease as well:
"Following the therapy, the CAR-T cell numbers rapidly increased and remained circulating in her system. This then resulted in a rapid depletion of B-cells and autoantibodies thought to be the cause of the autoimmune symptoms. Just six months after the treatment, Thu-Thao V is in complete remission and has returned to sports, something that she was unable to do while the joint pain, heart palpitations, and renal issues were present. She no longer requires drugs, and all her symptoms have disappeared.
"This is a massive breakthrough in immunotherapy, presenting an in vivo use of CAR-T cell therapy to put a young girl with a severe autoimmune disease into complete remission for a long period of time after therapy. The researchers now hope to continue this work into a clinical trial on people with autoimmune diseases." https://www.iflscience.com/health-and-medicine/experimental-immunotherapy-cures-girl-of-autoimmune-disease/?fbclid=IwAR0T72aJt-61XiY5qjfd8eqEPaojKPxeY6K5wYykfOKUtKEelCa-sqR-iTg

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