Moderna booster on the way?
I’m still awaiting approval of the Moderna booster. But this preprint suggests that approval may be forthcoming soon:
From the abstract: “Antibody neutralization titers against B.1.351 and P.1 variants measured by SARS-CoV-2 pseudovirus neutralization (PsVN) assays before the booster vaccinations, approximately 6 to 8 months after the primary series, were low or below the assay limit of quantification, although geometric mean titers versus the wild-type strain remained above levels likely to be protective. Two weeks after the booster vaccinations, titers against the wild-type original strain, B.1.351, and P.1 variants increased to levels similar to or higher than peak titers after the primary series vaccinations.”
From the Discussion: “Prior to the boost, neutralization titers of 198 and 304 in the Part B and Part C cohorts remained significant, at levels predicted to be protective against the original Wuhan-Hu-1 isolate . . . all trial participants, including those that had undetectable titers against the variant viruses, had robust neutralization titers in both the wild-type and variant assays two weeks after the booster.”
https://www.medrxiv.org/content/10.1101/2021.05.05.21256716v1.full.pdf
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