Moderna v Pfizer

 I ended up in the Moderna Phase III trial because that was the vaccine being trialed at our Vaccine Center. The clinic is on the first floor of the same building where my office is, so it was easy. I ended up in the vaccine arm, not the placebo arm, by chance, although everyone was offered the vaccine last January. Next week, it will be a full year since my first injection.

Both the Moderna and Pfizer vaccines are mRNA for the SARS-CoV-2 spike protein. I was intrigued by this approach and that was one of several reasons I volunteered.

The data so far show that both vaccines are comparable in their protection, even with the Delta variant, although by several metrics the Moderna vaccine has a small numerical edge in protection. Since the vaccines themselves are nearly identical, the most logical thing to infer is that the higher dose in the Moderna vaccine explains the difference.

The durability of protection is still unclear, since the vaccines are so new. Data out to six months indicates a highly durable response, supporting the view that a strong memory T cell response is elicited.

https://www.medpagetoday.com/infectiousdisease/covid19vaccine/93982?xid=nl_mpt_DHE_2021-08-11&eun=g1700464d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=Daily%20Headlines%20Top%20Cat%20HeC%20%202021-08-11&utm_term=NL_Daily_DHE_dual-gmail-definition

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